Histology

At Sentinel Healthcare CIC, patient safety is our highest priority. Where clinically appropriate, tissue removed during your private dermatology procedure may be sent for histology (histopathology). Histology is the microscopic examination of tissue by a specialist pathologist and is an important part of confirming a diagnosis and determining whether any further treatment is required.

Our private dermatology clinics in Plymouth, Exeter, Barnstaple, North Devon and South East Cornwall work closely with accredited NHS histopathology laboratories to ensure every specimen is carefully analysed when required.

What Is Histology?

Histology, also known as histopathology, is the laboratory examination of tissue removed during a minor surgical procedure.

Although many skin lesions can be confidently diagnosed during your consultation, examining the tissue under a microscope provides additional reassurance and can confirm the exact diagnosis.

Histology helps identify whether a skin lesion is:

• Benign (non-cancerous).
• Pre-cancerous.
• Malignant (cancerous).
• Completely removed during surgery.

When Is Histology Recommended?

Histology may be recommended following the removal of a variety of skin lesions, including:

• Moles (naevi).
• Sebaceous, epidermoid and pilar cysts.
• Lipomas.
• Skin tags where clinically indicated.
• Seborrhoeic keratoses.
• Other benign or suspicious skin lesions.

Your clinician will advise whether histological examination is appropriate based on your individual circumstances and the appearance of the lesion.

What Happens to My Tissue Sample?

If your tissue is sent for histology, the process is straightforward and carefully managed.

Following your procedure:

1. The tissue is placed into a preservative solution (usually formalin).
2. The specimen is labelled with your details and relevant clinical information.
3. It is securely transported to an accredited histopathology laboratory.
4. A specialist Consultant Pathologist prepares microscopic slides and carefully examines the tissue.
5. A detailed written report is returned to your Sentinel Healthcare clinician for review.

Every specimen is handled in accordance with strict clinical governance and laboratory standards.

What Does the Histology Report Show?

The histology report provides important clinical information, which may include:

• A definitive diagnosis.
• Confirmation of whether the lesion is benign or malignant.
• Whether the lesion has been completely removed (clear surgical margins).
• Whether any further treatment or monitoring is recommended.
• Any additional microscopic findings that may influence your ongoing care.

Why Is Histology Important?

Histology provides valuable reassurance for both patients and clinicians.

It helps to:

• Confirm or refine the clinical diagnosis.
• Identify any unexpected abnormalities.
• Determine whether further treatment is required.
• Confirm that a lesion has been completely removed where appropriate.
• Form part of your permanent medical record.

In many cases, histology confirms that a lesion is completely benign, providing valuable peace of mind.

How Long Do Histology Results Take?

Most routine histology results are returned within 4 to 5 weeks, although turnaround times can vary depending on laboratory workloads and the complexity of the specimen.

Urgent samples are prioritised where clinically necessary.

Once your results have been reviewed, one of our clinicians will contact you to explain the findings. A copy of the histology report will also be shared with your GP, ensuring your medical records remain complete and up to date.

Which Laboratory Analyses My Sample?

Where histology is required, tissue samples are analysed by the specialist Histopathology teams at:

• Derriford Hospital, Plymouth.
• North Devon District Hospital.

These experienced laboratory teams provide detailed microscopic analysis to support accurate diagnosis and ongoing patient care.